克罗烷二萜类化合物的昆虫拒食活性。

Insect antifeedant activity of clerodane diterpenoids.

作者信息

Sosa M E, Tonn C E, Giordano O S

机构信息

Departamento de Bioquímica y Ciencias Biológicas, Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, Argentina.

出版信息

J Nat Prod. 1994 Sep;57(9):1262-5. doi: 10.1021/np50111a012.

DOI:10.1021/np50111a012

PMID:7798961

Abstract

Fourteen clerodane-type diterpenoids isolated from plants in the genera Baccharis, Teucrium, and Salvia were assayed for antifeedant activity against Tenebrio molitor larvae in order to establish structure-activity relationships. Among the compounds tested, furanoditerpenes with alpha, beta-unsaturated-gamma-lactone moieties, or C-4-epoxy substitution with C-5-methylacetoxy or C-12-acyloxy functionalities, exhibited maximal antifeedant and repellent activities.

摘要

从巴卡里斯属、香科科属和鼠尾草属植物中分离出14种克罗烷型二萜类化合物，对黄粉虫幼虫进行拒食活性测定，以建立构效关系。在所测试的化合物中，具有α，β-不饱和-γ-内酯部分的呋喃二萜，或具有C-5-甲基乙酰氧基或C-12-酰氧基官能团的C-4-环氧取代物，表现出最大的拒食和驱避活性。