Ma W, Stahlhut R W, Adams T L, Park G L, Evans W A, Blumenthal S G, Gomez G A, Nieder M H, Hylands P J
PHYTOpharmaceuticals, Inc., San Carlos, California 94070-3312.
J Nat Prod. 1994 Sep;57(9):1320-4. doi: 10.1021/np50111a027.
From cell cultures of Taxus chinensis var. mairei, yunnanxane [2 alpha, 5 alpha, 10-beta triacetoxy-14 beta-(2'-methyl-3'-hydroxyl)-butyryloxy-4(20),11-taxadiene, [1], and four new homologous esters, 2 alpha, 5 alpha, 10 beta, 14 beta- tetra-acetoxy-4(20),11-taxadiene [2], 2 alpha, 5 alpha, 10 beta- triacetoxy-14 beta-propionyloxy-4(20),11-taxadiene [3], 2 alpha, 5 alpha, 10 beta- triacetoxy-14 beta-isobutyryloxy-4(20),11- taxadiene [4], and 2 alpha, 5 alpha, 10 beta- triacetoxy-14 beta-(2'-methyl)-butyryloxy-4(20),11- taxadiene [5] have been isolated. Their structures were determined by spectroscopic methods.
从中国红豆杉南方红豆杉的细胞培养物中，分离得到了云南紫杉烷[2α,5α,10-β-三乙酰氧基-14β-(2'-甲基-3'-羟基)-丁酰氧基-4(20),11-紫杉二烯，[1]，以及四种新的同系酯，2α,5α,10β,14β-四乙酰氧基-4(20),11-紫杉二烯[2]，2α,5α,10β-三乙酰氧基-14β-丙酰氧基-4(20),11-紫杉二烯[3]，2α,5α,10β-三乙酰氧基-14β-异丁酰氧基-4(20),11-紫杉二烯[4]，和2α,5α,10β-三乙酰氧基-14β-(2'-甲基)-丁酰氧基-4(20),11-紫杉二烯[5]。通过光谱方法确定了它们的结构。
