Hashimoto K, Hamamoto Y, Taniguchi T, Kumon M, Osako T, Kim Y
Department of Respiratory Disease, Kyoto City Hospital, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1994 Sep;32(9):888-93.
The prognosis for Wegener's granulomatosis (W-G) is good if it is diagnosed early and a combination of corticosteroids and cytotoxic drugs is given. During the past fourteen years, we were encountered four cases of W-G, three were systemic and one was limited. Of the three patients, with systemic disease, two died of myocardial infarction caused by a delay in diagnosis and one died of fulminant renal and respiratory failure. Only the one patient with a limited form of the disease survived for more than 5 years. We emphasize the importance of early diagnosis with consideration of the systemic features of W-G.
如果韦格纳肉芽肿（W-G）能早期诊断并给予皮质类固醇和细胞毒性药物联合治疗，其预后良好。在过去的十四年里，我们遇到了4例W-G患者，其中3例为全身性，1例为局限性。在3例全身性疾病患者中，2例因诊断延误死于心肌梗死，1例死于暴发性肾和呼吸衰竭。只有1例局限性疾病患者存活超过5年。我们强调早期诊断并考虑W-G全身特征的重要性。
