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配对数据卡方分析的错误使用。

The incorrect use of Chi-square analysis for paired data.

作者信息

Hoffman J I

出版信息

Clin Exp Immunol. 1976 Apr;24(1):227-9.

PMID:780018
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1538510/
Abstract

When results are classified in categories (for example, improved and unimproved, reactive and non-reactive) and the same patients are examined by two different treatments or two different tests, then the correct statistical analysis is by McNemars test. More often a Chi-square analysis is used; this is not only incorrect but also leads to erroneous conclusions.

摘要

当结果被分类(例如,改善和未改善、反应性和非反应性),并且相同的患者接受两种不同的治疗或两种不同的测试时,那么正确的统计分析是使用 McNemar 检验。更常见的是使用卡方分析;这不仅不正确,还会导致错误的结论。

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本文引用的文献

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N Engl J Med. 1975 Aug 21;293(8):388-9. doi: 10.1056/NEJM197508212930806.
2
Correlations among cutaneous reactivity to DNCB, PHA-induced lymphocyte blastogenesis and peripheral blood E rosettes.皮肤对二硝基氯苯的反应性、PHA诱导的淋巴细胞增殖反应与外周血E花环之间的相关性。
Clin Exp Immunol. 1975 Feb;19(2):327-33.