Lewallen S
International Eye Foundation, Blantyre, Malawi, Africa.
Ophthalmology. 1994 Nov;101(11):1801-4. doi: 10.1016/s0161-6420(94)31099-2.
The objective was to describe the complications and outcomes of herpes zoster ophthalmicus in a population of young Africans with a high seroprevalence of human immunodeficiency virus type 1 in which treatment often is delayed and in which antiviral drugs are not available.
Twenty-seven patients with herpes zoster ophthalmicus presenting consecutively to a large urban hospital were examined and followed. Treatment was limited to that which was locally available.
Visual outcomes were poor. Sixty-six percent of eyes had final visual acuity less than 20/60. Forty percent had light perception or no light perception visual acuity. Severe keratouveitis and corneal perforation were common and responsible for most poor visual outcomes.
Young Africans with herpes zoster ophthalmicus are at a high risk for significant visual loss.
目的是描述在1型人类免疫缺陷病毒血清阳性率高的年轻非洲人群中，眼部带状疱疹的并发症和结局，在该人群中治疗常常延迟且无法获得抗病毒药物。
对连续到一家大型城市医院就诊的27例眼部带状疱疹患者进行检查并随访。治疗限于当地可获得的治疗方法。
视力预后较差。66%的眼睛最终视力低于20/60。40%的眼睛有光感或无光感视力。严重的角膜葡萄膜炎和角膜穿孔很常见，是导致大多数视力预后不良的原因。
患有眼部带状疱疹的年轻非洲人有显著视力丧失的高风险。
