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用于新生儿预防结核病的卡介苗(“1331哥本哈根”菌株)临床测试报告(作者译)

[Report of clinical testing of BCG vaccine (Strain "1331 Copenhagen") for vaccination of newborns against tuberculosis (author's transl)].

作者信息

Nevermann L, Beutnagel H, Schumann K

出版信息

Geburtshilfe Frauenheilkd. 1976 Jun;36(6):481-4.

PMID:780189
Abstract

BCG vaccination with the vaccine "1331 Copenhagen" in various concentrations was carried out in 129 newborns. Control examinations were conducted to establish the complication rate and the percentage of tuberculin-positive children. Complications, either locally or in regional lymphatic areas, did not appear. The conversion rate increased with the number of viable units pro dose of vaccine. A vaccine with a concentration of about 250,000 units of vaccine pro dose is recommended for additional clinical testing.

摘要

对129名新生儿接种了不同浓度的“哥本哈根1331”卡介苗。进行对照检查以确定并发症发生率和结核菌素阳性儿童的百分比。未出现局部或区域淋巴区域的并发症。转化率随每剂疫苗中活单位数量的增加而提高。建议使用每剂约含250,000单位疫苗的疫苗进行进一步的临床试验。

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