Nevermann L, Beutnagel H, Schumann K
Geburtshilfe Frauenheilkd. 1976 Jun;36(6):481-4.
BCG vaccination with the vaccine "1331 Copenhagen" in various concentrations was carried out in 129 newborns. Control examinations were conducted to establish the complication rate and the percentage of tuberculin-positive children. Complications, either locally or in regional lymphatic areas, did not appear. The conversion rate increased with the number of viable units pro dose of vaccine. A vaccine with a concentration of about 250,000 units of vaccine pro dose is recommended for additional clinical testing.
对129名新生儿接种了不同浓度的“哥本哈根1331”卡介苗。进行对照检查以确定并发症发生率和结核菌素阳性儿童的百分比。未出现局部或区域淋巴区域的并发症。转化率随每剂疫苗中活单位数量的增加而提高。建议使用每剂约含250,000单位疫苗的疫苗进行进一步的临床试验。
