Papp J P, Levine E J, Thomas F B
Department of Internal Medicine, Ohio State University Hospitals, Columbus.
Am J Gastroenterol. 1995 Jan;90(1):141-5.
Primary linitis plastica of the colon or rectum is a rare entity. Only 85 cases of this type cancer have been reported in the English medical literature. We report two cases, including the oldest known patient presenting uniquely with a sigmoid volvulus and another patient presenting with fecal incontinence and perianal pain. Linitis plastica of the colon or rectum is characterized by presentation in younger patients and is associated with metastatic disease, a high mortality, and insidious growth, often making detection difficult. A high degree of suspicion must therefore be held; a low threshold for endoscopic and echoendoscopic diagnostic intervention also should be maintained. Endoscopic ultrasound provides a unique view of its circumferential infiltrating pattern for diagnosis and staging, but further experience is necessary to establish whether the early use of endoscopic ultrasound favorably impacts mortality.
原发性结肠或直肠皮革胃是一种罕见的疾病。英文医学文献中仅报道过85例此类癌症病例。我们报告了两例病例，其中包括已知年龄最大的仅以乙状结肠扭转为独特表现的患者，以及另一例表现为大便失禁和肛周疼痛的患者。结肠或直肠皮革胃的特点是多见于年轻患者，与转移性疾病、高死亡率和隐匿性生长相关，这常常使诊断变得困难。因此，必须保持高度怀疑；对于内镜和超声内镜诊断干预也应保持较低的阈值。内镜超声为其环形浸润模式的诊断和分期提供了独特视角，但要确定早期使用内镜超声是否对死亡率有积极影响，还需要更多经验。
