Osipova N A, Beresnev V A, Abuzarova G R, Loseva N A, Edeleva N V, Novikova O V
Anesteziol Reanimatol. 1994 Jul-Aug(4):41-5.
Efficacy of nonsteroid antiinflammatory drugs in the system of postoperative intensive care of patients to relieve postoperative pain, reduce the aftereffects of surgical injury to tissues, and thromboembolic complications is pathogenetically validated. A high efficacy of water-soluble acetylsalicylic acid, acelysin, in patients after extensive oncologic surgery is demonstrated. Acelysin had a good analgesic effect without side effects and permitted reducing the dose of opiates for postoperative analgesia by 3 times in comparison with the control group. Acelysin infusion in the immediate postoperative period reliably prevented thromboembolic complications and ruled out the necessity of resorting to heparin. Acelysin is regarded as a special nonopiate component of postoperative intensive care noticeably improving its efficacy.
非甾体抗炎药在患者术后重症监护系统中缓解术后疼痛、减轻手术对组织的损伤后遗症以及血栓栓塞并发症的疗效已得到病理生理学验证。已证明水溶性乙酰水杨酸（阿塞利辛）在广泛肿瘤手术后的患者中具有高效性。阿塞利辛具有良好的镇痛效果且无副作用，与对照组相比，可使术后镇痛的阿片类药物剂量减少3倍。术后即刻输注阿塞利辛可可靠地预防血栓栓塞并发症，且无需使用肝素。阿塞利辛被视为术后重症监护的一种特殊非阿片类成分，可显著提高其疗效。
