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急诊科胸痛患者快速诊断与治疗中心。

A rapid diagnostic and treatment center for patients with chest pain in the emergency department.

作者信息

Gibler W B, Runyon J P, Levy R C, Sayre M R, Kacich R, Hattemer C R, Hamilton C, Gerlach J W, Walsh R A

机构信息

Department of Emergency Medicine, University of Cincinnati College of Medicine, OH.

出版信息

Ann Emerg Med. 1995 Jan;25(1):1-8. doi: 10.1016/s0196-0644(95)70347-0.

DOI:10.1016/s0196-0644(95)70347-0
PMID:7802357
Abstract

STUDY OBJECTIVE

To evaluate a comprehensive diagnostic 9-hour evaluation (Heart ER Program) for patients with possible acute ischemic coronary syndromes.

DESIGN

Retrospective review of consecutive patients.

SETTING

Urban tertiary care emergency department.

PARTICIPANTS

A total of 1,010 patients with symptoms suggestive of acute ischemic coronary syndrome was enrolled in the Heart ER Program over the first 32 months of operation. Patients with history of coronary artery disease, hemodynamic instability, acute ST-segment elevation or depression of more than 1 mm, or a clinical syndrome consistent with unstable angina were directly admitted to the hospital.

INTERVENTION

Patients underwent serial testing for creatine kinase (CK-MB) on presentation to the Heart ER and 3, 6, and 9 hours later with continuous 12-lead ECGs/serial ST-segment trend monitoring for 9 hours. Two-dimensional echocardiography and graded exercise testing were performed in the ED after the 9-hour evaluation period.

RESULTS

Of 1,010 patients, 829 (82.1%) were released home from the ED; 153 (15.1%) required admission for further cardiac evaluation. Fifty-two of 153 (33.9%) admitted patients were found to have a cardiac cause for their symptoms; 43 had acute ischemic coronary syndromes (12, acute myocardial infarction; 31, angina or unstable angina).

CONCLUSION

The Heart ER program provides an effective method for evaluating low- to moderate-risk patients with possible acute ischemic coronary syndrome in the ED setting.

摘要

研究目的

评估针对可能患有急性缺血性冠状动脉综合征患者的一项全面的9小时诊断评估(心脏急诊程序)。

设计

对连续患者进行回顾性研究。

地点

城市三级医疗急诊科。

参与者

在该心脏急诊程序运行的前32个月中,共有1010名有急性缺血性冠状动脉综合征症状的患者被纳入。有冠状动脉疾病史、血流动力学不稳定、急性ST段抬高或压低超过1毫米,或临床综合征符合不稳定型心绞痛的患者直接入院。

干预措施

患者在进入心脏急诊时、3小时后、6小时后及9小时后接受肌酸激酶(CK-MB)的系列检测,并进行连续9小时的12导联心电图/系列ST段趋势监测。在9小时评估期后于急诊科进行二维超声心动图和分级运动试验。

结果

1010名患者中,829名(82.1%)从急诊科出院回家;153名(15.1%)需要入院进行进一步的心脏评估。153名入院患者中有52名(33.9%)被发现其症状有心脏病因;43名患有急性缺血性冠状动脉综合征(12名急性心肌梗死;31名心绞痛或不稳定型心绞痛)。

结论

心脏急诊程序为在急诊科环境中评估可能患有急性缺血性冠状动脉综合征的低至中度风险患者提供了一种有效方法。

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1
A rapid diagnostic and treatment center for patients with chest pain in the emergency department.急诊科胸痛患者快速诊断与治疗中心。
Ann Emerg Med. 1995 Jan;25(1):1-8. doi: 10.1016/s0196-0644(95)70347-0.
2
Comparison of a 6-hour and 9-hour protocol for evaluation of moderate-to-low risk chest pain patients in an emergency department diagnostic unit.急诊科诊断单元中评估中低风险胸痛患者的6小时和9小时方案比较。
Singapore Med J. 2001 Feb;42(2):52-6.
3
Early CK-MB elevations predict ischemic events in stable chest pain patients.早期肌酸激酶同工酶(CK-MB)升高可预测稳定型胸痛患者的缺血事件。
Acad Emerg Med. 1994 Jan-Feb;1(1):9-16. doi: 10.1111/j.1553-2712.1994.tb02794.x.
4
Serial creatine kinase-MB results are a sensitive indicator of acute myocardial infarction in chest pain patients with nondiagnostic electrocardiograms: the second Emergency Medicine Cardiac Research Group Study.连续肌酸激酶同工酶结果是心电图无诊断意义的胸痛患者急性心肌梗死的敏感指标:第二项急诊医学心脏研究组研究。
Acad Emerg Med. 1997 Sep;4(9):869-77. doi: 10.1111/j.1553-2712.1997.tb03812.x.
5
Early detection of acute myocardial infarction in patients presenting with chest pain and nondiagnostic ECGs: serial CK-MB sampling in the emergency department.对胸痛且心电图无诊断意义的患者急性心肌梗死的早期检测:急诊科连续检测肌酸激酶同工酶(CK-MB)
Ann Emerg Med. 1990 Dec;19(12):1359-66. doi: 10.1016/s0196-0644(05)82598-3.
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An evaluation of a chest pain diagnostic protocol to exclude acute cardiac ischemia in the emergency department.急诊科用于排除急性心肌缺血的胸痛诊断方案评估。
Arch Intern Med. 1997 May 26;157(10):1085-91.
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The Erlanger chest pain evaluation protocol: a one-year experience with serial 12-lead ECG monitoring, two-hour delta serum marker measurements, and selective nuclear stress testing to identify and exclude acute coronary syndromes.埃尔朗格胸痛评估方案:一项为期一年的经验,采用连续12导联心电图监测、两小时增量血清标志物测量以及选择性核素负荷试验来识别和排除急性冠脉综合征。
Ann Emerg Med. 2002 Dec;40(6):584-94. doi: 10.1067/mem.2002.129506.
8
Acute myocardial infarction in chest pain patients with nondiagnostic ECGs: serial CK-MB sampling in the emergency department. The Emergency Medicine Cardiac Research Group.心电图无诊断意义的胸痛患者的急性心肌梗死:急诊科连续检测肌酸激酶同工酶。急诊医学心脏研究小组。
Ann Emerg Med. 1992 May;21(5):504-12. doi: 10.1016/s0196-0644(05)82515-6.
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Multicenter study of creatine kinase-MB use: effect on chest pain clinical decision making.肌酸激酶同工酶-MB应用的多中心研究:对胸痛临床决策的影响
Acad Emerg Med. 1996 Jan;3(1):7-15. doi: 10.1111/j.1553-2712.1996.tb03295.x.
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Serial ECGs are less accurate than serial CK-MB results for emergency department diagnosis of myocardial infarction.对于急诊科心肌梗死的诊断,系列心电图检查不如系列肌酸激酶同工酶(CK-MB)检测结果准确。
Ann Emerg Med. 1992 Dec;21(12):1445-50. doi: 10.1016/s0196-0644(05)80057-5.

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