Resemblance of blast responses of C3H/HeJ mouse and rabbit spleen lymphocytes to B-cell mitogenic components of E. coli cell walls.

Nude mice lymphocytes were stimulated by heat-killed E.coli bacterial cells as well as by various components of their cell walls such as lipopolysaccharide, peptidoglycan and lipoprotein. Only bacterial cells, peptidoglycan and lipoprotein induce a high stimulation of C3H/HeJ mouse and rabbit lymphocytes. These data show the resemblance of mutant C3H/HeJ mice to rabbits with regard to blast response induced by various mitogenic components of E.Coli cell walls.