[黄连汤对大鼠实验性胃损伤及家鸽止吐作用的药理研究]
[Pharmacological studies on the effects of huanglian decoction on experimental gastric lesions in rats and antiemetic in pigeons].
作者信息
Qin C L, Liu J Y, Cheng Z M
机构信息
Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing.
出版信息
Zhongguo Zhong Yao Za Zhi. 1994 Jul;19(7):427-30, 448.
PMID:7802953
Abstract
The results showed that Huanglion decoction has protective effect on ethanol-,HCl- and aspirin-induced gastric hemorrhagic lesions in rats and antemetic effect on CuSO4-induced vomiting in pigeons. A dose of 27g/(kg.d) po applied in mice showed no toxic action. This dose is 400 times that of clinical application.
摘要
结果表明，黄 lion 汤对乙醇、盐酸和阿司匹林诱导的大鼠胃出血性损伤具有保护作用，对硫酸铜诱导的鸽子呕吐具有止吐作用。以 27g/(kg·d)的剂量灌胃给予小鼠未显示出毒性作用。该剂量是临床应用剂量的 400 倍。
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