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生牡蛎壳与煅牡蛎壳抗溃疡作用的比较研究

[A comparative study on anti-ulcer action of unprepared and calcined oyster shell].

作者信息

Nie S Q, Li T L, Jiang W J, Xue B Y, Liang A H, Li G Q, Yang Q

机构信息

Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing.

出版信息

Zhongguo Zhong Yao Za Zhi. 1994 Jul;19(7):405-7, 446.

PMID:7802944
Abstract

On experimental gastric ulcer models induced by 0.6mol/L HCl, ethyl alcohol or ligation of the pylorus, the preventive effects of unprepared oyster shell, calcined oyster shell 1(900 degrees C, 1h), calcined oyster shell 2(350 degrees C, 8h) were compared in Wistar rats. Results showed that antagonistic effects of calcined oyster shell 1 to the drug pathogenesis of peptic ulcer and the incidence of peptic ulcer after ligation of the pylorus were markedly greater.

摘要

在由0.6mol/L盐酸、乙醇或幽门结扎诱导的实验性胃溃疡模型上,比较了生牡蛎壳、煅牡蛎壳1(900℃,1小时)、煅牡蛎壳2(350℃,8小时)对Wistar大鼠的预防作用。结果表明,煅牡蛎壳1对消化性溃疡药物发病机制及幽门结扎后消化性溃疡发生率的拮抗作用明显更强。

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