Wagner F M, Reichenspurner H, Uberfuhr P, Weiss M, Fingerle V, Reichart B
Department of Cardiac Surgery, University of Munich, Germany.
J Heart Lung Transplant. 1994 Sep-Oct;13(5):916-8.
Protozoal infections such as toxoplasmosis are known complications in heart transplant recipients. Diagnosis of the disease is often difficult. This article describes the course of a patient who had a febrile illness with leukocytosis and neurologic disorders after heart transplantation; all microbiologic and serologic tests of the peripheral blood and the cerebrospinal fluid failed to identify the responsible pathogen. Infection with Toxoplasma gondii was finally diagnosed by endomyocardial biopsy. We conclude that in heart transplant recipients with infections of unclear origin and neurologic disorders, endomyocardial biopsy may be helpful in the diagnosis, especially in cases of toxoplasmosis.
诸如弓形虫病等原生动物感染是心脏移植受者已知的并发症。该病的诊断往往很困难。本文描述了一名心脏移植后出现发热性疾病、白细胞增多和神经功能障碍患者的病程；外周血和脑脊液的所有微生物学和血清学检测均未能识别出致病病原体。最终通过心内膜心肌活检诊断为弓形虫感染。我们得出结论，对于病因不明且有神经功能障碍的心脏移植受者，心内膜心肌活检可能有助于诊断，尤其是在弓形虫病病例中。
