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[原位心脏移植术后由弓形虫和烟曲霉引起的心肌炎]

[Myocarditis caused by Toxoplasma gondii and Aspergillus fumigatus after orthotopic heart transplantation].

作者信息

Völker H, Sigmund M, Kropff M, Hürter T, Kemnitz J, Kirkpatrick C J, Hanrath P

机构信息

Medizinische Klinik I, RWTH Aachen.

出版信息

Z Kardiol. 1991 May;80(5):359-62.

PMID:1872010
Abstract

This report describes the case of a 56-year-old patient, who died 53 days after orthotopic heart transplantation due to myocarditis caused by infection with Aspergillus fumigatus and Toxoplasma gondii. Aspergillosis was diagnosed by transthoracic needle aspiration of a pulmonary infiltration. Endomyocardial biopsy showed toxoplasma pseudocysts. Autopsy revealed myocardial infection with both infectious agents. Despite specific therapy, myocarditis determined the fatal outcome in this case. The value of invasive techniques for specific diagnosis of infectious diseases in immunocompromised patients is discussed.

摘要

本报告描述了一名56岁患者的病例,该患者在原位心脏移植术后53天因感染烟曲霉和弓形虫导致心肌炎而死亡。通过经胸针吸肺部浸润灶诊断为曲霉菌病。心内膜活检显示有弓形虫假囊肿。尸检发现心肌感染了这两种病原体。尽管进行了特异性治疗,但心肌炎仍是该病例的致命结局。文中讨论了侵入性技术在免疫功能低下患者传染病特异性诊断中的价值。

相似文献

1
[Myocarditis caused by Toxoplasma gondii and Aspergillus fumigatus after orthotopic heart transplantation].[原位心脏移植术后由弓形虫和烟曲霉引起的心肌炎]
Z Kardiol. 1991 May;80(5):359-62.
2
Fulminant toxoplasmosis in a heart transplant recipient.一名心脏移植受者的暴发性弓形虫病。
Pathol Res Pract. 2001;197(3):211-5. doi: 10.1078/0344-0338-00036.
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Toxoplasmosis after heart transplantation: diagnosis by endomyocardial biopsy.心脏移植后弓形虫病:通过心内膜心肌活检进行诊断
J Heart Lung Transplant. 1994 Sep-Oct;13(5):916-8.
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Myocardial calcification after orthotopic heart transplantation.原位心脏移植后的心肌钙化
J Heart Transplant. 1988 Jul-Aug;7(4):304-8.
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Aspergillus terreus myocarditis: report of a case and review of the literature.土曲霉性心肌炎:一例报告及文献复习
Am J Cardiovasc Pathol. 1990;3(3):275-9.
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Treatment of serious heart failure by transplantation in giant cell myocarditis diagnosed by endomyocardial biopsy.经心内膜心肌活检诊断为巨细胞性心肌炎后,通过移植治疗严重心力衰竭。
J Heart Lung Transplant. 1994 May-Jun;13(3):543-5.
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Ten-year experience with endomyocardial biopsy in myocarditis presenting with congestive heart failure: frequency, pathologic characteristics, treatment and follow-up.心肌活检诊断充血性心力衰竭合并心肌炎的十年经验:发生率、病理特征、治疗及随访
G Ital Cardiol. 1997 Mar;27(3):209-23.
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Nosocomial outbreak of Aspergillus fumigatus infection among patients in a renal unit?肾病科患者中烟曲霉感染的医院内暴发?
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Acute rejection and heart infection rates in FK 506- versus cyclosporine A-treated heart transplant recipients: an endomyocardial biopsy pathologic study.FK506与环孢素A治疗的心脏移植受者的急性排斥反应和心脏感染率:一项心内膜心肌活检病理研究
J Heart Lung Transplant. 1997 Sep;16(9):982-4.
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Bronchial-pulmonary artery fistula after unilateral lung transplantation: a case report.单侧肺移植术后支气管-肺动脉瘘:一例报告
J Heart Lung Transplant. 1997 Jun;16(6):674-7.

引用本文的文献

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The differential agglutination test as a diagnostic aid in cases of toxoplasmic lymphadenitis.鉴别凝集试验作为弓形虫性淋巴结炎病例的诊断辅助手段。
J Clin Microbiol. 2007 May;45(5):1463-8. doi: 10.1128/JCM.01781-06. Epub 2007 Feb 21.
2
Sulfadiazine therapy for toxoplasmosis in heart transplant recipients decreases cyclosporine concentration.
Clin Investig. 1992 Sep;70(9):752-4. doi: 10.1007/BF00180742.