Pienta K J
Meyer L. Prentis Comprehensive Cancer Center, Wayne State University School of Medicine, Michigan Cancer Foundation, Detroit 48201.
In Vivo. 1994 May-Jun;8(3):419-22.
Prostate cancer exists as two different clinical entities; a "latent" or "histologic" form and a clinically evident form. While the prevalence of histologic prostate cancer is similar around the world, the prevalence of clinical cancer varies dramatically from country to country. This suggests that promotional events which contribute in the transformation of histologic cancer to clinically important cancer vary from country to country and population to population. The ultimate goal of epidemiologic studies is to identify risk factors, i.e., promotional agents, for prostate cancer and to use this knowledge for disease prevention strategies.
“潜伏”或“组织学”形式以及临床显性形式。虽然组织学前列腺癌在世界各地的患病率相似,但临床癌症的患病率在不同国家之间差异巨大。这表明促使组织学癌症转变为具有临床重要性癌症的促进因素因国家和人群而异。流行病学研究的最终目标是确定前列腺癌的风险因素,即促进因素,并将这一知识用于疾病预防策略。