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高血糖症伴对侧纹状体和丘脑血流增加时出现偏身舞蹈症。

Hemichorea in hyperglycemia associated with increased blood flow in the contralateral striatum and thalamus.

作者信息

Nabatame H, Nakamura K, Matsuda M, Fujimoto N, Shio H

机构信息

Department of Neurology, Medical Center, Shiga.

出版信息

Intern Med. 1994 Aug;33(8):472-5. doi: 10.2169/internalmedicine.33.472.

DOI:10.2169/internalmedicine.33.472
PMID:7803913
Abstract

We studied a patient with hyperglycemia who developed choreic involuntary movements in the right extremities using single photon emission computed tomography (SPECT) with 123I-N-isopropyl-p-iodoamphetamine. SPECT revealed an increased blood flow in the left striatum and thalamus. Through the control of blood glucose and the administration of haloperidol, the hemichorea was resolved, and the increased blood flow in the striatum and thalamus disappeared. These findings suggest that the increased blood flow, which probably indicates increased neuron activity in the striatum and thalamus, is an underlying pathophysiological state in hemichorea.

摘要

我们研究了一名患有高血糖症且右上肢出现舞蹈样不自主运动的患者,使用123I-N-异丙基-p-碘安非他明单光子发射计算机断层扫描(SPECT)进行检查。SPECT显示左侧纹状体和丘脑血流增加。通过控制血糖和给予氟哌啶醇,偏侧舞蹈症得到缓解,纹状体和丘脑血流增加的情况消失。这些发现表明,血流增加可能表明纹状体和丘脑神经元活动增加,是偏侧舞蹈症潜在的病理生理状态。

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