[The sensitivity of tumor cells to low doses of antitumor preparations].

The anticancer activity of water solutions of nitrosomethylurea, adriblastin and cisplatin at low and extra low concentrations (to 10(-15) M) was studied in the mice with experimentally induced tumor. Single and multiple administration of these drugs at extra low doses changed the life duration. Nitrosomethylurea (10(-15) M) increased the life duration by 20-86%. Nitrosomethylurea at extra low concentrations modifies the organism and tumor sensitivity to subsequent action of a high dose of this drug.