Parc R, Chevallier J M, Faucheron J L, Frileux P
Hôpital Saint-Antoine, Service de Chirurgie générale, Paris.
Chirurgie. 1993;119(8):392-6.
Between 1960 and 1988, 83 patients (38 men, 43 women) underwent colectomy and ileorectal anastomosis (IRA) for severe colonic or rectal Crohn's disease. The mean age at IRA was 28.5 years. The mean interval from diagnosis was 4 years. There were two post-operative deaths. Among the 81 survivors 5 patients who had a covering ileostomy have never had their stomas closed and 24 patients required exclusion or excision of their IRA and rectum. (= 10 defunctioning IRA, 14 proctectomies with definitive ileostomy). The mean interval between IRA and the creation of a permanent ileostomy was 4.1 years. The mean interval between the onset of problems following IRA and permanent ileostomy was 2 years. 25 patients had perianal lesions prior to IRA. 5 of these patients had unhealed perianal disease at IRA and 7 required defunctioning ileostomy (28%). The need for rectal excision or exclusion following IRA was not related to the presence of perianal disease prior to IRA but functional results were worse. 33 patients developed perianal lesions following their IRA, among whom 19 required exclusion or excision of the rectum. Failure of IRA was then significantly higher amongst those who developed lesions following IRA. Rectal preservation after IRA may be proposed with success to patients with a healthy rectum or with minimal or moderate proctitis, even if there is perianal disease that could be safely treated before IRA. In this last setting the patient has to be informed of the risk of rectal preservation and the possible risk of requiring ulterior protectomy.
1960年至1988年间,83例患者(38例男性,43例女性)因严重结肠或直肠克罗恩病接受了结肠切除术和回肠直肠吻合术(IRA)。IRA手术时的平均年龄为28.5岁。从诊断到手术的平均间隔时间为4年。术后有2例死亡。在81名幸存者中,5例做了覆盖性回肠造口术的患者从未关闭过造口,24例患者需要切除或排除IRA及直肠(=10例功能性IRA,14例直肠切除术并永久性回肠造口术)。IRA与永久性回肠造口术之间的平均间隔时间为4.1年。IRA术后出现问题至行永久性回肠造口术的平均间隔时间为2年。25例患者在IRA术前有肛周病变。其中5例患者在IRA时肛周疾病未愈合,7例需要做功能性回肠造口术(28%)。IRA术后直肠切除或排除的必要性与IRA术前肛周疾病的存在无关,但功能结果较差。33例患者在IRA术后出现肛周病变,其中19例需要切除或排除直肠。IRA术后出现病变的患者中IRA失败率明显更高。对于直肠健康或直肠炎轻微或中度的患者,即使存在可在IRA术前安全治疗的肛周疾病,也可成功建议保留直肠。在这种情况下,必须告知患者保留直肠的风险以及可能需要进一步行直肠切除术的风险。