Daude F, Frileux P, Penna C, Tiret E, Parc R
Service de Chirurgie Digestive, Hôpital Saint-Antoine, Paris.
Ann Chir. 1993;47(10):1014-9.
In order to precise the indications and results of this procedure, we assessed 11 cases of transformation of ileorectal anastomosis (IRA) to ileal pouch-anal anastomosis (IPAA) in ulcerative colitis (UC). These 5 men and 6 women had undergone IRA at a mean age of 31 years, 33 months after the diagnosis of UC (range 3-120). Four of these IRA, excluded by an ileostomy, had never been in function: the cause was severe persistent proctitis in 2 cases and anastomotic leakage and peritonitis in 2 cases. The other 7 IRA had been in function during a mean period of 25 months (range 6-45) and were reoperated because of anal sepsis (1 case), low rectal stenosis (1 case), disabling proctitis (4 cases) and rectal dysplasia (1 case). No patient had specific pathologic signs of Crohn's disease. The 11 IPAA were complicated by pelvic sepsis in 3 cases; surgical drainage succeeded in 1 case, but the 2 others needed pouch excision and terminal ileostomy. The diagnosis of Crohn's disease was eventually made in these 2 patients. The 9 patients with functioning IPAA, at a mean follow-up of 40 months (range 12-60), had 5.2 stools per 24 h (range 2-12), 5 patients had no nocturnal stooling, and 6 had a perfect continence. One patient had disabling chronic pouchitis. In conclusion, proctectomy with IPAA is always feasible when a previous IRA for UC had failed or offers poor results, but should be rejected in case of anal involvement, as that may suggest Crohn's disease. This procedure is followed by similar functional results than after primary IPAA.
为明确该手术的适应证和效果,我们评估了11例溃疡性结肠炎(UC)患者回肠直肠吻合术(IRA)转为回肠袋肛管吻合术(IPAA)的情况。这11例患者中,5例男性,6例女性,IRA手术时的平均年龄为31岁,诊断UC后33个月(范围3 - 120个月)。其中4例IRA因行回肠造口术而未发挥功能:2例是由于严重持续性直肠炎,2例是由于吻合口漏和腹膜炎。另外7例IRA发挥功能的平均时间为25个月(范围6 - 45个月),因肛门感染(1例)、低位直肠狭窄(1例)、致残性直肠炎(4例)和直肠发育异常(1例)而再次手术。所有患者均无克罗恩病的特异性病理表现。11例IPAA中有3例发生盆腔感染;1例经手术引流成功,但另外2例需要切除肠袋并行末端回肠造口术。这2例患者最终被诊断为克罗恩病。9例IPAA功能良好的患者,平均随访40个月(范围12 - 60个月),24小时排便5.2次(范围2 - 12次),5例患者无夜间排便,6例患者控便良好。1例患者有致残性慢性袋炎。总之,当UC患者先前的IRA手术失败或效果不佳时,行IPAA直肠切除术总是可行的,但如果肛门受累则应避免,因为这可能提示克罗恩病。该手术的功能结果与初次IPAA术后相似。