Zhang C F, Zhang S L
Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Yan Ke Za Zhi. 1994 Sep;30(5):335-7.
The fellow eyes of 30 cases with unilateral wet age related macular degeneration (ARMD) were followed up for more than 5 years. On fundus and fluorescein angiographic examinations, it is demonstrated that a half of them showed normal fundi and the rest of them showed drusens and/or retinal pigment epithelial (RPE) changes. During the follow-up period, 4 cases developed subretinal neovascular membrane at the 5th, 6th, 10th, and 11th year, respectively. Of them, essentially normal fundi were in 2 cases, macular drusens in 1 case and RPE changes in another case at the first visit. The results indicate that the fellow eye of unilateral wet ARMD may develop subretinal neovascular membrane after a long period of time.
对30例单侧湿性年龄相关性黄斑变性(ARMD)患者的对侧眼进行了5年以上的随访。眼底和荧光素血管造影检查显示,其中一半患者眼底正常,其余患者出现玻璃膜疣和/或视网膜色素上皮(RPE)改变。在随访期间,分别有4例患者在第5年、第6年、第10年和第11年发生了视网膜下新生血管膜。其中,初诊时眼底基本正常的有2例,黄斑玻璃膜疣的有1例,RPE改变的有1例。结果表明,单侧湿性ARMD的对侧眼在长时间后可能会发生视网膜下新生血管膜。