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[兔实验性外伤性白内障中谷胱甘肽过氧化物酶活性及丙二醛水平的动态变化]

[The dynamic changes in glutathione peroxidase activity and malondialdehyde level in experimental traumatic cataract in rabbit].

作者信息

Hong M G, Jiang S Y, Wang J

机构信息

Department of Biochemistry, Anhui Medical University, Hefei.

出版信息

Zhonghua Yan Ke Za Zhi. 1994 Sep;30(5):379-81.

PMID:7805545
Abstract

Glutathione peroxidase activity (GSH-PX) and malondialdehyde (MDA) level of experimental traumatic cataract in rabbit were determined at various intervals after needling. GSH-PX activities decreased in the lens after perforated trauma from 8 hours to 21 days, meanwhile the MDA level increased markedly. The results demonstrate that free radicals are involved in the formation of traumatic cataract.

摘要

在针刺后的不同时间间隔,测定兔实验性外伤性白内障的谷胱甘肽过氧化物酶活性(GSH-PX)和丙二醛(MDA)水平。穿孔性创伤后8小时至21天,晶状体中GSH-PX活性下降,同时MDA水平显著升高。结果表明自由基参与了外伤性白内障的形成。

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