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吡罗昔康与β-环糊精的超分子包合物:实验室动物药理特性综述

Supermolecular inclusion of piroxicam with beta-cyclodextrin: a review of its pharmacological properties in laboratory animals.

作者信息

Lister R E, Acerbi D, Cadel S

机构信息

Phylax Health Care, Beaconsfield, UK.

出版信息

Eur J Rheumatol Inflamm. 1993;12(4):6-11.

PMID:7805705
Abstract

Piroxicam-beta-cyclodextrin is a novel NSAID; it is a supermolecular inclusion complex designed to improve the risk:benefit ratio of piroxicam. In animal studies it has been shown to be as effective as piroxicam as an anti-inflammatory and analgesic agent but with a more rapid onset of action and reduced gastropathic effects.

摘要

吡罗昔康-β-环糊精是一种新型非甾体抗炎药;它是一种超分子包合物,旨在改善吡罗昔康的风险效益比。动物研究表明,它作为抗炎和镇痛药与吡罗昔康效果相当,但起效更快,且胃肠道不良反应减少。

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