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正常及非整倍体人类淋巴细胞对电离辐射的适应性反应。

Adaptive response to ionizing radiation in normal and aneuploid human lymphocytes.

作者信息

Kalina I, Konecná H, Némethová G, Raceková N

机构信息

Department of Medical Biology, Medical Faculty, Safarik University, Kosice.

出版信息

Folia Biol (Praha). 1994;40(3):119-23.

PMID:7805933
Abstract

The ability to induce an adaptive response by low doses of gamma rays was studied in normal and trisomic lymphocytes (47, XX or XY, +21). The results indicate the presence of an adaptive response in lymphocytes of 3 normal donors, but in lymphocytes of 5 donors with trisomy 21 no significant adaptive response after irradiation with a low dose of gamma rays was found. There was similar chromosomal radiosensitivity in normal and trisomic lymphocytes (47, XX or XY, +21) irradiated with 1.50 Gy at the 48th hour after stimulation.

摘要

在正常和三体淋巴细胞(47, XX或XY, +21)中研究了低剂量γ射线诱导适应性反应的能力。结果表明,3名正常供体的淋巴细胞中存在适应性反应,但在5名21三体供体的淋巴细胞中,低剂量γ射线照射后未发现明显的适应性反应。在刺激后第48小时用1.50 Gy照射的正常和三体淋巴细胞(47, XX或XY, +21)中,染色体放射敏感性相似。

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