Kalina I, Konecná H, Némethová G, Raceková N
Department of Medical Biology, Medical Faculty, Safarik University, Kosice.
Folia Biol (Praha). 1994;40(3):119-23.
The ability to induce an adaptive response by low doses of gamma rays was studied in normal and trisomic lymphocytes (47, XX or XY, +21). The results indicate the presence of an adaptive response in lymphocytes of 3 normal donors, but in lymphocytes of 5 donors with trisomy 21 no significant adaptive response after irradiation with a low dose of gamma rays was found. There was similar chromosomal radiosensitivity in normal and trisomic lymphocytes (47, XX or XY, +21) irradiated with 1.50 Gy at the 48th hour after stimulation.
在正常和三体淋巴细胞(47, XX或XY, +21)中研究了低剂量γ射线诱导适应性反应的能力。结果表明,3名正常供体的淋巴细胞中存在适应性反应,但在5名21三体供体的淋巴细胞中,低剂量γ射线照射后未发现明显的适应性反应。在刺激后第48小时用1.50 Gy照射的正常和三体淋巴细胞(47, XX或XY, +21)中,染色体放射敏感性相似。