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美国男性和女性近期的癌症模式:职业研究线索

Recent cancer patterns among men and women in the United States: clues for occupational research.

作者信息

Devesa S S, Grauman D J, Blot W J

机构信息

Biostatistics Branch, Epidemiology and Biostatistics Program, National Cancer Institute, Bethesda, MD 20892.

出版信息

J Occup Med. 1994 Aug;36(8):832-41.

PMID:7807262
Abstract

Investigation of cancer rates--including trends over time, geographic variations, and differences by race, gender, and age--may identify patterns suggesting environmental exposures of potential occupational origin. National mortality data spanning the 40-year period from 1950 to 1989 were used to assess the patterns of several cancers for which occupational components have been identified among men, including cancers of the lung and bladder, non-Hodgkin's lymphoma, and leukemia, and for cancers of particular concern to women, such as breast and ovarian cancer, but for which occupational factors have not been well characterized. Newly available preliminary data show substantial geographic variation in cancer mortality rates at the county level during the 1970s and 1980s. Future analyses of the patterns, correlations with industrial indicators, and analytic studies should be fruitful in identifying occupational and other risk factors for cancers among women.

摘要

对癌症发病率的调查——包括随时间的趋势、地理差异以及种族、性别和年龄差异——可能会发现一些模式,这些模式表明潜在的职业性环境暴露。利用1950年至1989年这40年期间的全国死亡率数据,评估了几种癌症的发病模式,这些癌症在男性中已确定有职业因素,包括肺癌、膀胱癌、非霍奇金淋巴瘤和白血病,以及女性特别关注的癌症,如乳腺癌和卵巢癌,但这些癌症的职业因素尚未得到充分描述。最新可得的初步数据显示,在20世纪70年代和80年代,县级癌症死亡率存在很大的地理差异。未来对这些模式、与工业指标的相关性以及分析研究进行分析,应该会有助于确定女性癌症的职业和其他风险因素。

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