Ma F, Lee D J, Fleming L E, Dosemeci M
Department of Epidemiology and Public Health, University of Miami School of Medicine, FL 33101, USA.
J Occup Environ Med. 1998 Dec;40(12):1134-8. doi: 10.1097/00043764-199812000-00014.
A mortality odds ratio (MOR) study of race-specific cancer risk among firefighters was conducted using 1984-1993 death certificate data from 24 states. The Bureau of the Census Index of Industries and Occupations was used to code occupation on death certificates. The overall cancer mortality was slightly elevated among white firefighters (MOR = 1.1; 95% confidence interval [CI] = 1.1-1.2), but the increase in overall cancer mortality among black firefighters was not significant (MOR = 1.2; 95% CI = 0.9-1.5). Only prostate cancer risk was elevated in both groups (whites: MOR = 1.2; 95% CI = 1.0-1.3; blacks: MOR = 1.9; 95% CI = 1.2-3.2). Among white firefighters, elevated site-specific cancer mortality risks were found for the following cancer sites: lip (MOR = 5.9; 95% CI = 1.9-18.3), pancreas (MOR = 1.2; 95% CI = 1.0-1.5), soft tissue sarcoma (MOR = 1.6; 95% CI = 1.0-2.7), melanoma (MOR = 1.4; 95% CI = 1.0-1.9), kidney and renal pelvis (MOR = 1.3; 95% CI = 1.0-1.7), non-Hodgkin's lymphoma (MOR = 1.4; 95% CI = 1.1-1.7), and Hodgkin's disease (MOR = 2.4; 95% CI = 1.4-4.1). We also observed a slightly elevated risk for bronchus and lung cancer (MOR = 1.1; 95% CI = 1.0-1.2). Among black firefighters, excess risks were found for cancers of the brain and central nervous system (MOR = 6.9; 95% CI = 3.0-16.0), colon (MOR = 2.1; 95% CI = 1.1-4.0), and nasopharynx (MOR = 7.6; 95% CI = 1.3-46.4). Future studies are needed to confirm the existence of differential cancer mortality risks among firefighters of different race/ethnic subpopulations.
利用来自24个州的1984 - 1993年死亡证明数据，对消防员中特定种族的癌症风险进行了死亡率比值比（MOR）研究。使用人口普查局的行业和职业索引对死亡证明上的职业进行编码。白人消防员的总体癌症死亡率略有升高（MOR = 1.1；95%置信区间[CI] = 1.1 - 1.2），但黑人消防员的总体癌症死亡率升高并不显著（MOR = 1.2；95% CI = 0.9 - 1.5）。两组中只有前列腺癌风险升高（白人：MOR = 1.2；95% CI = 1.0 - 1.3；黑人：MOR = 1.9；95% CI = 1.2 - 3.2）。在白人消防员中，发现以下癌症部位的特定部位癌症死亡率风险升高：唇部（MOR = 5.9；95% CI = 1.9 - 18.3）、胰腺（MOR = 1.2；95% CI = 1.0 - 1.5）、软组织肉瘤（MOR = 1.6；95% CI = 1.0 - 2.7）、黑色素瘤（MOR = 1.4；95% CI = 1.0 - 1.9）、肾脏和肾盂（MOR = 1.3；95% CI = 1.0 - 1.7）、非霍奇金淋巴瘤（MOR = 1.4；95% CI = 1.1 - 1.7）和霍奇金病（MOR = 2.4；95% CI = 1.4 - 4.1）。我们还观察到支气管和肺癌风险略有升高（MOR = 1.1；95% CI = 1.0 - 1.2）。在黑人消防员中，发现脑和中枢神经系统癌症（MOR = 6.9；95% CI = 3.0 - 16.0）、结肠癌（MOR = 2.1；9% CI = 1.1 - 4.0）和鼻咽癌（MOR = 7.6；95% CI = 1.3 - 46.4）的风险增加。需要进一步的研究来证实不同种族/族裔亚群体的消防员中存在不同的癌症死亡率风险。
