Tateishi O, Okamura T, Itou T, Murakami M, Suda T, Nishimuta I, Obata S, Nagata T
Department of Internal Medicine (IV), Jikei University School of Medicine, Tokyo, Japan.
Jpn Circ J. 1994 Nov;58(11):831-5. doi: 10.1253/jcj.58.831.
Eighty-five coronary artery patients examined using an ambulatory electrocardiogram-respiration monitoring system (AERMS) in which a respiratory sensor was strapped to the right upper abdominal wall. Apnea was defined as a cessation of abdominal wall movement lasting at least 10 sec. Sleep-related breathing disorder (SRBD) was diagnosed if at least 30 apneic episodes were observed during sleep. The cardiac events evaluated during follow-up included occurrence of sudden death, myocardial infarction and ventricular tachycardia. SRBD was detected in 9 of 85 patients (11%). There were more patients with low EF (EF < 50%) in the SRBD group than in the non-SRBD group (p < 0.01). During follow-up for a mean period of 18.4 +/- 7.6 months after ambulatory recording, four of nine (44%) patients in the SRBD group had cardiac events, compared with only four of 79 (6%) patients in the non-SRBD group (p < 0.001). Thus, coronary artery patients who were complicated with SRBD showed poor cardiac function and had a high incidence of cardiac events.
85例冠状动脉疾病患者使用动态心电图-呼吸监测系统（AERMS）进行检查，该系统的呼吸传感器绑在右上腹壁。呼吸暂停定义为腹壁运动停止持续至少10秒。如果在睡眠期间观察到至少30次呼吸暂停发作，则诊断为睡眠相关呼吸障碍（SRBD）。随访期间评估的心脏事件包括猝死、心肌梗死和室性心动过速的发生。85例患者中有9例（11%）检测到SRBD。SRBD组中左心室射血分数（EF）低（EF<50%）的患者比非SRBD组更多（p<0.01）。在动态记录后平均随访18.4±7.6个月期间，SRBD组9例患者中有4例（44%）发生心脏事件，而非SRBD组79例患者中只有4例（6%）发生心脏事件（p<0.001）。因此，合并SRBD的冠状动脉疾病患者心脏功能较差，心脏事件发生率较高。
