Nakamura K, Isobe T, Okusaki K, Niitani K, Murakami I, Yoshida Y, Fujiwara Y, Yamaoka N, Hasegawa K, Yamakido M
Second Department of Internal Medicine, Hiroshima University School of Medicine, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1994 Aug;32(8):814-8.
A 51-year-old man was admitted to our hospital with a chief complaint of cough. His chest X-ray and CT scan revealed enlargement of a left hilar lymph node. However, no primary lesion was apparent in the rest of the lung. Bronchofiberscopic findings were essentially normal. At surgery the mass was determined to be an enlarged lymph node (No. 11). No apparent malignant lesion was identified in the lung. Postoperative pathological examination showed small cell carcinoma in a part of the No. 11 lymph node. Despite a thorough systemic examination, no primary foci were detected. We have been following up this patient with chemotherapy for the approximately 2 year period since the operation, but no primary lesions have been detected as yet. Therefore, we speculate that this patient is a very rare case of primary unknown T0N1M0 lung cancer.
一名51岁男性因咳嗽主诉入院。他的胸部X光和CT扫描显示左肺门淋巴结肿大。然而，肺部其他部位未发现明显的原发病变。纤维支气管镜检查结果基本正常。手术中确定肿块为肿大的淋巴结（11组）。肺部未发现明显的恶性病变。术后病理检查显示11组淋巴结部分为小细胞癌。尽管进行了全面的系统检查，但未发现原发灶。自手术以来，我们对该患者进行了约2年的化疗随访，但至今仍未发现原发病变。因此，我们推测该患者是原发性不明T0N1M0肺癌的极为罕见病例。
