Shibuya Y, Kitamura S
Department of Pulmonary Medicine, Jichi Medical School, Tochigi, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1994 Aug;32(8):819-23.
A case of primary pulmonary cryptococcosis is reported. A 76-year-old man, without underlying disease or immunological abnormalities, was admitted to the hospital. Chest X-ray revealed diffuse infiltrative shadows considered at first to be community-acquired pneumonia. A diagnosis of pulmonary cryptococcosis was performed using fluconazole, miconazole and transbronchial inhalation of amphotericin B. Cryptococcal antigen detection was performed by two latex agglutination methods: Crypto-test and Sero-direct test (Eiken-test). Comparing the results of the two tests, sensitivity was superior with the Sero-direct test, but the correlation between the titers of the two tests was good.
报告了一例原发性肺隐球菌病病例。一名76岁男性，无基础疾病或免疫异常，入院治疗。胸部X线显示弥漫性浸润阴影，最初考虑为社区获得性肺炎。使用氟康唑、咪康唑和经支气管吸入两性霉素B对肺隐球菌病进行诊断。通过两种乳胶凝集法进行隐球菌抗原检测：Crypto-test和Sero-direct test（荣研检测）。比较两种检测结果，Sero-direct test的敏感性更高，但两种检测的滴度之间相关性良好。
