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[白细胞干扰素在化脓性 - 败血症性疾病中的疗效]

[The efficacy of leukinferon in suppurative-septic diseases].

作者信息

Spivak N Ia, Ganova L A, Iakovenko L F, Kravchuk B A, Makarov A V, Krivokhatskaia L D, Simonova A A, Belotskiĭ S M

出版信息

Klin Khir (1962). 1994(5):56-8.

PMID:7807907
Abstract

In the complex of treatment of purulent-septic diseases leukinferon at a dose of 300 IU/kg was used according to the following scheme: 3 injections with the 48 h interval between injections. The effect of leukinferon mainly on the function of neutrophil granulocytes and subpopulation of T-lymphocytes was established. Together with clinico-laboratory data indicative of the effectiveness of treatment, normalization of interferon status and decrease in the level of a circulating factor of tumour necrosis in seriously ill patients was observed.

摘要

在化脓性败血症性疾病的综合治疗中,按照以下方案使用剂量为300 IU/kg的白细胞干扰素:注射3次,每次注射间隔48小时。确定了白细胞干扰素主要对中性粒细胞功能和T淋巴细胞亚群的作用。除了有表明治疗有效性的临床实验室数据外,还观察到重症患者的干扰素状态恢复正常以及循环肿瘤坏死因子水平降低。

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