Rosenow E C
Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota 55905.
Mayo Clin Proc. 1995 Jan;70(1):45-9. doi: 10.1016/S0025-6196(11)64664-8.
The frequently encountered disorder of venous thromboembolism (VTE) can cause serious morbidity and even death. Nevertheless, in more than 70% of patients who die of pulmonary embolism (PE), the diagnosis is not considered before death. Thus, clinicians should have a high index of suspicion for VTE, especially in high-risk patients. Some risk factors for VTE are a recent surgical procedure and general anesthesia, immobilization, congestive heart failure, previous PE, pregnancy, and oral contraceptive use. Before therapy can be initiated, a definitive diagnosis of VTE must be established. An algorithm for assessing patients with possible VTE is presented; decisions about proceeding with various studies are based primarily on the clinician's degree of suspicion for the presence of PE and the findings on a ventilation-perfusion scan. Elevation of the patient's legs before, during, and after a surgical procedure is a simple measure that may substantially decrease the occurrence of PE.
常见的静脉血栓栓塞症(VTE)可导致严重发病甚至死亡。然而,在超过70%死于肺栓塞(PE)的患者中,死亡前未考虑到该诊断。因此,临床医生对VTE应保持高度怀疑指数,尤其是在高危患者中。VTE的一些危险因素包括近期手术和全身麻醉、制动、充血性心力衰竭、既往PE、妊娠及口服避孕药使用。在开始治疗前,必须确立VTE的明确诊断。本文给出了评估可能患有VTE患者的算法;关于进行各种检查的决策主要基于临床医生对PE存在的怀疑程度以及通气-灌注扫描结果。手术前、手术期间和手术后抬高患者腿部是一项简单措施,可大幅降低PE的发生率。