Eriksson S E, Johansson I, Lind B, Olsson J E
Medicinska Kliniken, Falu Lasarett, Falun.
Lakartidningen. 1994 Nov 23;91(47):4393-7.
Interest in Binswanger's disease has increased during the past decade, owing to the possibility of detecting white matter changes with computerised and magnetic resonance tomography. This paper consists in a summary of clinical symptoms and signs and possible diagnostic criteria, discussion of differential diagnosis, and the presentation of two own cases. Both patients manifested mild dementia and gait disturbance, and one had frequent drop attacks. Severe supra- and infra-tentorial white matter changes were present in both cases. It is important to consider a possible diagnosis of Binswanger's disease, as treatment of the appropriate risk factors may prevent or delay the development of dementia.
在过去十年中,由于计算机断层扫描和磁共振断层扫描能够检测到白质变化,对宾斯旺格病的关注度有所增加。本文总结了临床症状和体征以及可能的诊断标准,讨论了鉴别诊断,并介绍了两个病例。两名患者均表现为轻度痴呆和步态障碍,其中一名患者频繁跌倒发作。两例均存在严重的幕上和幕下白质变化。考虑宾斯旺格病的可能诊断很重要,因为对适当风险因素的治疗可能预防或延缓痴呆的发展。