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[农药引起的过敏性疾病:3例报告]

[Allergic diseases caused by pesticides: 3 case reports].

作者信息

Assini R, Fracchiolla F, Ravalli C, Nava C

机构信息

Istituto di Medicina del Lavoro, Università di Milano.

出版信息

Med Lav. 1994 Jul-Aug;85(4):321-6.

PMID:7808348
Abstract

Current pesticide exposure levels can induce a state of sensitization in exposed workers and only in exceptional situations cause severe intoxication. Three cases are reported--one suffering from urticaria/angio-edema, one from asthma and the other from oculo-rhinitis. Only one subject was atopical. The substances to which sensitization was found were Cynoxamil, Mancozeb, Thiophanate, Seccatutto for the first case, Paraquat for the second and Dodine for the third subject. The results suggest the need to extend allergological tests also to pesticides when workers, or subjects in any case exposed, show clinical signs with suspected immunological pathogenesis. Furthermore, in order to reduce the number of new cases of pesticide allergy, a more severe control also of subjects exposed to low doses is proposed.

摘要

当前的农药接触水平可使接触农药的工人产生致敏状态,仅在特殊情况下会导致严重中毒。本文报告了3例病例——1例患有荨麻疹/血管性水肿,1例患有哮喘,另1例患有眼鼻炎。仅1例为特应性体质。第1例病例中发现致敏的物质为环辛酰胺、代森锰锌、甲基托布津、噻菌灵,第2例为百草枯,第3例为多果定。结果表明,当工人或任何接触农药的个体出现疑似免疫发病机制的临床症状时,有必要将变应性试验扩展至农药。此外,为了减少农药过敏的新病例数量,建议对低剂量接触农药的个体也进行更严格的管控。

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