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急性疟疾后疫苗接种免疫反应受损。

Impairment of the immune response to vaccination after acute malaria.

作者信息

Williamson W A, Greenwood B M

出版信息

Lancet. 1978 Jun 24;1(8078):1328-9. doi: 10.1016/s0140-6736(78)92403-0.

DOI:10.1016/s0140-6736(78)92403-0
PMID:78096
Abstract

Children with acute malaria were vaccinated with Salmonella typhi and meningococcal vaccines at varying times after the onset of their illness. The immune response to both vaccines was depressed when they were given on the day of presentation at hospital. Immune responsiveness to S. typhi vaccine was rapidly regained after treatment, but a month after the attack the immune response to meningococcal vaccine was still impaired.

摘要

患急性疟疾的儿童在发病后的不同时间接种了伤寒沙门菌疫苗和脑膜炎球菌疫苗。在入院当天接种这两种疫苗时,对它们的免疫反应均受到抑制。治疗后对伤寒沙门菌疫苗的免疫反应迅速恢复,但在发病一个月后,对脑膜炎球菌疫苗的免疫反应仍受损。

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