McCarthy J E, Brimacombe R
Department of Gene Expression, Gesellschaft Für Biotechnologische Forschung, Braunschweig, Germany.
Trends Genet. 1994 Nov;10(11):402-7. doi: 10.1016/0168-9525(94)90057-4.
Finding answers to the many open questions concerning the mechanism and control of prokaryotic translation remains one of the central challenges of molecular biology. In fact, recent experimental data even force us to reconsider aspects that were previously thought to be established fact. Here, we attempt a synthesis of new and not-so-new information, which leads to a revised and testable working hypothesis for translational initiation.
找到关于原核生物翻译机制及调控的诸多未决问题的答案，仍然是分子生物学的核心挑战之一。事实上，最近的实验数据甚至迫使我们重新审视一些以前被认为是既定事实的方面。在此，我们尝试综合新的和不太新的信息，从而得出一个经过修订且可验证的翻译起始工作假说。
