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[内质网在寄生肉孢子虫特殊细胞器形成中的作用]

[The role of the endoplasmic reticulum in the formation of specialized cellular organelles in parasitic Sarcosporidia].

作者信息

Radchenko A I

出版信息

Tsitologiia. 1994;36(4):359-64.

PMID:7809974
Abstract

A cytological study was made of participation of the endoplasmic reticulum in the formation of specific cell organelles in Sarcocystis muris zoites. The data presented in this paper confirm our earlier assumption (Radchenko, 1987) that the Golgi adjunct is a structure made of four membranes of the smooth endoplasmic reticulum (ER) channels. This organelle appeared to be available in all the three cell types recognized within the sarcocyst: metrocytes, intermediate cells and merozoites. In the dividing metrocytes and intermediate cells the Golgi adjunct is turning progressively in a polar ring, whose membranes are covered with a fibrillar material from which subpellicular microtubules are formed. It has been first shown that ER channels are involved in the formation of amylopectin granules and immediate glycoprotein regions around them. Large spiral structures, composed of the ER channels, were seen in the zoite cytoplasm. Besides, micronemes were also made of closely packed ER channels. It looks likely that individual micronemes may be connected to each other through these channels.

摘要

对内质网参与鼠肉孢子虫裂殖子中特定细胞器形成进行了细胞学研究。本文所呈现的数据证实了我们之前的假设(Radchenko,1987),即高尔基体附属物是由光滑内质网(ER)通道的四层膜构成的结构。在包囊内识别出的所有三种细胞类型(滋养母细胞、中间细胞和裂殖子)中似乎都有这种细胞器。在正在分裂的滋养母细胞和中间细胞中,高尔基体附属物逐渐转变为一个极环,其膜上覆盖着一种纤维状物质,从该物质中形成表膜下微管。首次表明内质网通道参与支链淀粉颗粒及其周围直接的糖蛋白区域的形成。在裂殖子细胞质中可见由内质网通道组成的大型螺旋结构。此外,微线体也是由紧密排列的内质网通道构成。看起来单个微线体可能通过这些通道相互连接。

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