Balslev T, Kristensen B, Ebbesen F, Schumacher H, Korsager B
Aalborg Sygehus, paediatrisk afdeling, Statens Seruminstitut, København.
Ugeskr Laeger. 1994 Oct 24;156(43):6378-80.
A case of septicaemia in a seven-day-old infant with a gentamicin-resistant strain of Enterobacter cloacae prompted an epidemiological survey in a neonatal unit. Another 18 patients harboured gentamicin-resistant Enterobacteriaceae without symptoms. Control of the outbreak was achieved by cohort nursing, strict hygiene and reduction of aminoglycoside consumption by 50%. Efficiency of the measures was monitored by weekly faecal samples from all patients. All strains produced the aminoglycoside modifying enzyme AAC(3)II. The resistance was plasmid-mediated.
一名7日龄婴儿感染阴沟肠杆菌庆大霉素耐药菌株导致败血症，这促使对一家新生儿病房进行了流行病学调查。另外18名患者携带庆大霉素耐药肠杆菌科细菌但无症状。通过分组护理、严格的卫生措施以及将氨基糖苷类药物的消耗量减少50%来控制疫情爆发。通过每周采集所有患者的粪便样本监测这些措施的效果。所有菌株均产生氨基糖苷类修饰酶AAC(3)II。这种耐药性是由质粒介导的。
