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[根据被动防御反应持续时间和神经肌肉兴奋性阈值选择的大鼠的神经激素特征]

[The neurohormonal characteristics of rats selected for the duration of the passive defense reaction and for the threshold of neuromuscular excitability].

作者信息

Alekhina T A, Shul'ga V A, Lopatina N G, Shiriaeva N V, Vaĭdo A I

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1994 Jul-Oct;44(4-5):837-41.

PMID:7810225
Abstract

Two strains of rats, "genetic catalepsy" and "low-threshold", simulating some human psychopathological symptoms, were compared. Levels of brain monoamines and blood corticosterone and testosterone showed no common features in the strains studied. The levels of dopamine in amygdala and testosterone blood levels in rats of the two strains significantly deviated in opposite directions from corresponding controls. In "genetic catalepsy" strain noradrenaline content in striatum and diencephalon was decreased, and serotonin striatal level was increased.

摘要

对两种模拟某些人类精神病理症状的大鼠品系“遗传性僵住症”和“低阈值”进行了比较。在所研究的品系中,脑单胺、血液皮质酮和睾酮水平未表现出共同特征。两种品系大鼠杏仁核中的多巴胺水平和血液睾酮水平与相应对照组相比,在相反方向上有显著差异。在“遗传性僵住症”品系中,纹状体和间脑中去甲肾上腺素含量降低,纹状体中血清素水平升高。

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