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低频电刺激下PQS对豚鼠乳头肌的抗缺氧及抗葡萄糖缺乏作用

[Anti-hypoxia and anti-glucose deficiency effects of PQS on guinea pig papillary muscle in low frequency electrical stimulation].

作者信息

Yang S J, Li H, Wang Q J, Takeya K

机构信息

Norman Bethune University of Medical Sciences, changchun.

出版信息

Zhongguo Zhong Yao Za Zhi. 1994 Sep;19(9):560-2, 576.

PMID:7811372
Abstract

Panax quinquefolium saponin (PQS) increases the contractibility of papillary muscle of guinea pigs during electrical stimulation with frequency of 1/8-1/64Hz (P < 0.05). In Krebs-Henseleit solution purged with gas containing 95% N2 and 5% CO2 regardless of containing glucose or not, PQS (0.3mg/kg) has the effect of anti-hypoxia and anti-glucose deficiency (P < 0.05, P < 0.01) in the electrical stimulation with frequency of 1/8-1/64Hz.

摘要

西洋参皂苷(PQS)在1/8 - 1/64Hz频率的电刺激下可增强豚鼠乳头肌的收缩性(P < 0.05)。在通有含95% N2和5% CO2气体的Krebs - Henseleit溶液中,无论是否含有葡萄糖,PQS(0.3mg/kg)在1/8 - 1/64Hz频率的电刺激下均具有抗缺氧和抗葡萄糖缺乏的作用(P < 0.05,P < 0.01)。

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