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抗炎药:双氯芬酸的1-(2-羟乙基)吡咯烷鎓盐

Anti-inflammatory drugs: 1-(2-hydroxyethyl)pyrrolidinium salt of diclofenac.

作者信息

Castellari C, Sabatino P

机构信息

Dipartimento di Chimica G. Ciamician, Universitá di Bologna, Italy.

出版信息

Acta Crystallogr C. 1994 Nov 15;50 ( Pt 11):1723-6. doi: 10.1107/s0108270194003926.

DOI:10.1107/s0108270194003926
PMID:7811435
Abstract

In the solid-state structure of N-(2-hydroxyethyl)pyrrolidinium (2-[(2,6-dichlorophenyl)amino]phenyl)acetate, C6H14NO+. C14H10Cl2NO2-, the asymmetric unit contains two independent ion pairs differing mainly in the conformation of the cation. A complex network of inter- and intramolecular hydrogen bonds is present.

摘要

在N-(2-羟乙基)吡咯烷鎓(2-[(2,6-二氯苯基)氨基]苯基)乙酸酯C₆H₁₄NO⁺·C₁₄H₁₀Cl₂NO₂⁻的固态结构中,不对称单元包含两个主要在阳离子构象上不同的独立离子对。存在分子间和分子内氢键的复杂网络。

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