Honnor M J, Zubrick S R, Stanley F J
Institute for Child Health Research, Perth, Australia.
Eur J Epidemiol. 1994 Apr;10(2):181-8. doi: 10.1007/BF01730368.
The aim of the present study was to determine whether mothers reporting more life events experience more preterm births following both complicated and uncomplicated pregnancies. A Life Events Inventory was administered prospectively to women at high risk for poor obstetric and neonatal outcomes who took part in the Pregnancy Home Visiting Program (PHVP), a randomized controlled trial of the effect of a programme of antenatal home visits by midwives on the incidence of preterm birth. This study took place in Western Australia in the years 1984-1987. All women in the study had had a previous poor pregnancy outcome. The women were classified into two groups--those with complicated and those with uncomplicated pregnancies. Pregnancies classified as 'complicated' were defined as a pregnancy in which there was antenatal hospital admission(s) for hypertension, antepartum haemorrhage or other medical reason except for preterm birth. Pregnancies classified as 'uncomplicated' refer to all pregnancies without these complications. No significant association was found between life events and preterm birth although the total stress score for women with uncomplicated pregnancies almost reached significance, as did the number of life events for both women with complicated and women with uncomplicated pregnancies considered together. Life events were not shown to have a predictive relationship to preterm birth even when stratified by etiologically different groups. However, although stress was not an important predictor of preterm birth in this group of women at biological risk it may yet be so in a group at social risk.
本研究的目的是确定报告更多生活事件的母亲在复杂和非复杂妊娠后是否会经历更多早产情况。对参与妊娠家访项目（PHVP）的、有不良产科和新生儿结局高风险的女性前瞻性地实施了生活事件量表，该项目是一项关于助产士产前家访计划对早产发生率影响的随机对照试验。本研究于1984年至1987年在西澳大利亚进行。研究中的所有女性既往均有不良妊娠结局。这些女性被分为两组——复杂妊娠组和非复杂妊娠组。被归类为“复杂”的妊娠定义为因高血压、产前出血或除早产外的其他医学原因而在产前入院的妊娠。被归类为“非复杂”的妊娠指所有无这些并发症的妊娠。尽管非复杂妊娠女性的总压力得分几乎达到显著水平，以及复杂妊娠女性和非复杂妊娠女性合并在一起的生活事件数量也几乎达到显著水平，但未发现生活事件与早产之间存在显著关联。即使按病因不同的组进行分层，生活事件也未显示出与早产有预测关系。然而，尽管压力在这组有生物学风险的女性中不是早产的重要预测因素，但在有社会风险的女性组中可能是这样。
