Daudé F, Penna C, Tiret E, Frileux P, Hannoun L, Nordlinger B, Parc R
Service de Chirurgie Digestive, Hôpital Saint-Antoine, Paris.
Gastroenterol Clin Biol. 1994;18(5):462-8.
The aim of this study was to assess the results of ileal "J" pouch-anal anastomosis in ulcerative colitis. One hundred and fifty six patients operated on between 1983 and 1991 for ulcerative colitis were followed-up prospectively since the surgical procedure with a mean of 29 +/- 16 months (range: 6 to 92 months). There was no postoperative death. Forty-four patients (28%) presented 48 post-operative complications and 14 (9%) were reoperated. Twenty-five patients (16%) were reoperated because of a late complication. Three pouches had to be removed for untreatable fistulas which appeared to be related to a Crohn's disease in 2 cases; the reestablishment of a diverting loop ileostomy was mandatory in 2 further patients for anoperineal sepsis. The mean stool frequency at 1 year was 4.5 +/- 1.9; 40% of patients did not have nocturnal stooling. Daytime and nighttime continence were normal in 90.7% and 77.5% of cases respectively, 87% of patients considered their social life improved by the surgical cure of the disease. The results observed 5 years after the surgical procedure in 37 patients were similar to those observed at 1 year. Twenty-five patients (16%) presented one or several episodes of pouchitis, including 5 cases of chronic pouchitis. It is concluded that the treatment of ulcrerative colitis, ileal "J" pouch-anal anastomosis, is a safe and effective procedure which provides good functional results.
本研究的目的是评估溃疡性结肠炎患者回肠“J”袋肛管吻合术的效果。对1983年至1991年间因溃疡性结肠炎接受手术的156例患者自手术起进行前瞻性随访,平均随访时间为29±16个月(范围:6至92个月)。术后无死亡病例。44例患者(28%)出现48例术后并发症,14例(9%)接受了再次手术。25例患者(16%)因晚期并发症接受了再次手术。3个贮袋因无法治疗的瘘管而不得不切除,其中2例似乎与克罗恩病有关;另外2例患者因会阴区感染而必须再次建立转流性回肠造口术。术后1年时平均排便频率为4.5±1.9次;40%的患者无夜间排便。白天和夜间控便正常的病例分别为90.7%和77.5%,87%的患者认为手术治愈疾病后其社交生活得到改善。37例患者术后5年观察到的结果与术后1年观察到的结果相似。25例患者(16%)出现1次或多次贮袋炎发作,其中5例为慢性贮袋炎。结论是,溃疡性结肠炎的治疗方法——回肠“J”袋肛管吻合术是一种安全有效的手术,能取得良好的功能效果。