Roche H, Gibney M J
Department of Clinical Medicine, Trinity Health Sciences Centre, St. James' Hospital, Dublin, Ireland.
Int J Vitam Nutr Res. 1994;64(3):237-42.
Thirty-three male subjects were randomly allocated to one of three treatments which involved the consumption of 50 g/d of either one of three spreadable fats for twelve weeks. Group A consumed their normal spreadable fat; group B consumed a low-fat spread (40% fat wt/wt) which contained 8 g of fish oil per 100 g of product; group C consumed a high-fat spread (80% fat wt/wt) which contained 8 g of fish oil per 100 of product. Baseline levels of platelet phospholipid eicosapentaenoic acid (C20:5 n-3) were < 1.0% wt/wt at baseline in all groups and increased significantly (p < 0.05) in both groups receiving fish-oil containing spreads (12 week values of 1.5 +/- 0.5 for group B and 2.4 +/- 1.3 for group C). There was no change in the control group receiving their normal spreads. The ratio of all n-6; n-3 polyunsaturated fatty acids fell significantly in group B (12.5 +/- 3.1 v 1.7 +/- 1.9) and in group C (8.2 +/- 3.9 v 6.7 +/- 2.6), both of whom received fish oil. These two groups also achieved a significant (p < 0.05) increase in platelet phospholipid docosahexaenoic acid (C22: 6 n-3): 2.3 +/- 0.5 v 2.9 +/- 0.9 in group B and 2.3 +/- 0.6 v 3.1 +/- 0.9 in group C. The subjects encountered no important palatability or acceptability difficulties. These data show that, in individuals with low intakes of fatty fish, spreadable fats enriched with fish oil are a useful vehicle for ensuring adequate intakes of n-3 polyunsaturated fatty acids.
33名男性受试者被随机分配至三种处理方式中的一种，这三种处理方式包括连续12周每天食用50克三种可涂抹脂肪中的一种。A组食用其正常的可涂抹脂肪；B组食用低脂涂抹酱（脂肪含量为40%重量/重量），每100克产品中含有8克鱼油；C组食用高脂涂抹酱（脂肪含量为80%重量/重量），每100克产品中含有8克鱼油。所有组在基线时血小板磷脂二十碳五烯酸（C20:5 n-3）的水平均<1.0%重量/重量，在接受含鱼油涂抹酱的两组中均显著升高（p<0.05）（B组12周时的值为1.5±0.5，C组为2.4±1.3）。接受正常涂抹酱的对照组无变化。在接受鱼油的B组（12.5±3.1对1.7±1.9）和C组（8.2±3.9对6.7±2.6）中，所有n-6:n-3多不饱和脂肪酸的比例均显著下降。这两组的血小板磷脂二十二碳六烯酸（C22:6 n-3）也显著升高（p<0.05）：B组为2.3±0.5对2.9±0.9，C组为2.3±0.6对3.1±0.9。受试者未遇到重要的适口性或可接受性问题。这些数据表明，对于脂肪含量较低的鱼类摄入量较少的个体，富含鱼油的可涂抹脂肪是确保充足摄入n-3多不饱和脂肪酸的有用载体。
