文拉法辛与氟西汀治疗重度抑郁和 melancholia 住院患者的双盲对照研究。文拉法辛法国住院患者研究组。
A double-blind comparison of venlafaxine and fluoxetine in patients hospitalized for major depression and melancholia. The Venlafaxine French Inpatient Study Group.
作者信息
Clerc G E, Ruimy P, Verdeau-Pallès J
机构信息
Centre Hospitalier, Pontorson, France.
出版信息
Int Clin Psychopharmacol. 1994 Sep;9(3):139-43. doi: 10.1097/00004850-199409000-00001.
Abstract
The antidepressant efficacy and short-term safety of venlafaxine and fluoxetine were compared in 68 patients hospitalized with major depression and melancholia. Venlafaxine was superior in efficacy to fluoxetine; total scores for both the MADRS and the HAM-D were significantly (p < or = 0.05) lower in the venlafaxine group than in the fluoxetine group at Weeks 4 and 6. Overall tolerance was similar for the two treatments.
摘要
对68例因重度抑郁和 melancholia 住院的患者比较了文拉法辛和氟西汀的抗抑郁疗效及短期安全性。文拉法辛在疗效上优于氟西汀；在第4周和第6周时，文拉法辛组的MADRS和HAM-D总分显著（p≤0.05）低于氟西汀组。两种治疗的总体耐受性相似。
Zotero 插件