Knote G, Vielsäcker H, Mappes G
Med Klin. 1976 Jul 23;71(30):1235-8.
The necessity for thrombosis-prophylaxis is indisputable. The evaluation of our patients over a period of 2 years revealed results compatible with other authors. Due to its thrombocyte desaggregating action, acetyl-salicylic acid was found to have a definite effect on the thrombophilia by inhibiting the thrombocyte adhesiveness in a beginning thrombosis. It was shown that acetylsalicylic acid in combination with glycocoll is apparently superior to microencapsulated acetylic acid in terms of gastric tolerance. In a small number of patients the therapeutic efficiency was investigated and according to the platelets agglutination test, verified. Further investigations are planned in a major series of patients where acetylsalicylic acid with glycocoll was administered in respect to the treatment of rheumatic fever.
血栓预防的必要性是无可争议的。我们对患者进行了为期两年的评估，结果与其他作者的研究结果相符。由于乙酰水杨酸具有血小板解聚作用，通过抑制血栓形成初期的血小板黏附性，发现其对血栓形成倾向有明确作用。结果表明，就胃耐受性而言，乙酰水杨酸与甘氨酸组合明显优于微囊化乙酰水杨酸。在少数患者中对治疗效果进行了研究，并根据血小板凝集试验进行了验证。计划对大量患者进行进一步研究，这些患者将接受乙酰水杨酸与甘氨酸组合治疗风湿热。
