Gaar G G
Florida Poison Information and Toxicology Resource Center, Tampa.
J Fla Med Assoc. 1994 Nov;81(11):747-9.
Gastrointestinal decontamination therapy in the patient with accidental or intentional ingestion of toxic substances has been standard therapy for several decades, although based on theory of presumed action and benefit. As scientific knowledge accumulates in this area of clinical toxicology, old assumptions are being challenged by scientific evidence relating to gastric emptying, efficacy of activated charcoal, and usefulness of whole-bowel irrigation with polyethylene glycol electrolyte lavage solutions. An overview is presented of the scientific data now available. Although realizing the still unresolved controversies, a logical plan is described for gastrointestinal decontamination following acute overdose.
几十年来，对于意外或故意摄入有毒物质的患者，胃肠道去污疗法一直是标准疗法，尽管这是基于假定作用和益处的理论。随着临床毒理学这一领域科学知识的积累，关于胃排空、活性炭疗效以及聚乙二醇电解质灌洗溶液全肠灌洗的有用性等旧有假设正受到科学证据的挑战。本文对现有的科学数据进行了概述。尽管认识到仍存在未解决的争议，但还是描述了一个急性药物过量后胃肠道去污的合理方案。
