Hannan M A, Duck P, Nasim A
Mutat Res. 1976 Aug;36(2):171-6. doi: 10.1016/0027-5107(76)90005-1.
The induction of lethal sectoring and pure mutant clones by ultraviolet light has been studied in a homogeneous G1 population of Saccharomyces cerevisiae grown in a normal growth medium. At the lowest UV dose of 250 ergs, which corresponds to a shoulder in the survival curve, all mutants appeared as pure clones. At higher doses the frequency of mosaic mutants progressively increased. These results indicate a relationship between the highest frequency of complete mutants and the maximum repair activity. In addition, the frequency of lethal sectoring at all doses tested was too low to account for the origin of pure mutant clones.
在正常生长培养基中生长的酿酒酵母均匀G1群体中，研究了紫外线诱导致死性扇形化和纯突变克隆的情况。在最低紫外线剂量250尔格时，这对应于存活曲线中的一个肩部，所有突变体均以纯克隆形式出现。在较高剂量下，镶嵌突变体的频率逐渐增加。这些结果表明完全突变体的最高频率与最大修复活性之间存在关联。此外，在所有测试剂量下致死性扇形化的频率都太低，无法解释纯突变克隆的起源。
