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[通过从牛密质骨中提取的脂质“体外”形成矿物质和晶体]

[Mineral and crystal formation "in vitro" by lipids extracted from bovine compact bone].

作者信息

Ngoma Z, Devis R

出版信息

Pathol Biol (Paris). 1976 May;24(5):307-11.

PMID:781600
Abstract

In order to study the role of lipids in the calcification process of the bone tissue, lipids have been extracted from undecalcified compact bone of calves less than 6 months old and from cows or oxen more than 2 years of age. Lipids from each group have been fractionned in "polar" and "non polar" types. Each type of lipid was shown to promote the formation of calcium phosphate precipitates in vitro. But only the polar lipids from calves bone promoted the formation of crystallised calcium phosphates, similar to hydroxyapatite. The identification of both crystallised and amorphous precipitates has been achieved by X-ray diffraction and chemical analysis.

摘要

为了研究脂质在骨组织钙化过程中的作用,已从6个月龄以下小牛的未脱钙密质骨以及2岁以上母牛或公牛的未脱钙密质骨中提取脂质。每组脂质已被分为“极性”和“非极性”类型。已证明每种类型的脂质在体外均能促进磷酸钙沉淀的形成。但只有来自小牛骨骼的极性脂质能促进类似于羟基磷灰石的结晶磷酸钙的形成。已通过X射线衍射和化学分析实现了对结晶沉淀和无定形沉淀的鉴定。

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