小鼠腹腔巨噬细胞对瑞氏埃立克体进行吞噬作用时相关的呼吸爆发活动。

Respiratory burst activity associated with phagocytosis of Ehrlichia risticii by mouse peritoneal macrophages.

作者信息

Williams N M, Cross R J, Timoney P J

机构信息

Department of Veterinary Science, University of Kentucky, Lexington 40546.

出版信息

Res Vet Sci. 1994 Sep;57(2):194-9. doi: 10.1016/0034-5288(94)90057-4.

DOI:10.1016/0034-5288(94)90057-4

PMID:7817006

Abstract

Peritoneal macrophages from two strains of mice, BALB/c and C3H/HeN, were analysed by flow cytometry for a respiratory burst associated with the phagocytosis of Ehrlichia risticii. Resident murine peritoneal macrophages failed to respond with a respiratory burst after phagocytosing E risticii. In contrast, mice previously infected with E risticii yielded peritoneal macrophages that did generate a respiratory burst on phagocytosing ehrlichiae.

摘要

通过流式细胞术分析了两种品系小鼠（BALB/c和C3H/HeN）的腹膜巨噬细胞，以检测与吞噬瑞氏埃立克体相关的呼吸爆发。驻留的小鼠腹膜巨噬细胞在吞噬瑞氏埃立克体后未能产生呼吸爆发反应。相比之下，先前感染过瑞氏埃立克体的小鼠所产生的腹膜巨噬细胞在吞噬埃立克体时确实产生了呼吸爆发。