Rozé J C, Chambille B, Dehan M, Gaultier C
Neonatal Department, Hôpital Universitaire, Nantes, France.
Respir Physiol. 1994 Oct;98(2):227-39. doi: 10.1016/0034-5687(94)00056-5.
Measurements of oxygen uptake (VO2) and CO2 output (VCO2) are useful in critically ill patients. However, VO2 is not routinely measured in intensive care during mechanical ventilation (MV) especially in premature newborns. The present study describes a new method of measuring VO2 and VCO2 using a double open circuit which accounts for gas leaks around the uncuffed tracheal tube. The accuracy of the method was assessed with N2 and CO2 infusion. In case of leaks, VO2 and VCO2 measurement was significantly underestimated by the simple circuit method. This underestimation was not present with double circuit method. Five preterm newborns were studied. VO2 and VCO2 using the double open circuit were compared with the classic simple circuit. During MV, the mean underestimation assessed by the difference between simple and double circuit measurement was -12% (range from 0 to -29%) for VO2 and -14% (range 0 to -26%) for VCO2.
测量氧摄取量（VO2）和二氧化碳排出量（VCO2）对重症患者很有用。然而，在机械通气（MV）期间，尤其是在早产儿中，重症监护病房并不常规测量VO2。本研究描述了一种使用双开路测量VO2和VCO2的新方法，该方法考虑了无套囊气管导管周围的气体泄漏。用氮气和二氧化碳注入评估该方法的准确性。在存在泄漏的情况下，简单回路法会显著低估VO2和VCO2的测量值。双回路法不存在这种低估情况。研究了5名早产新生儿。将使用双开路测量的VO2和VCO2与经典的简单回路进行比较。在机械通气期间，通过简单回路和双回路测量之间的差异评估的平均低估率，VO2为-12%（范围为0至-29%），VCO2为-14%（范围为0至-26%）。
