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全肺切除术后的早期和长期结果。

Early and long-term results after completion pneumonectomy.

作者信息

Massard G, Lyons G, Wihlm J M, Fernoux P, Dumont P, Kessler R, Roeslin N, Morand G

机构信息

Department of Thoracic Surgery, Hôpitaux Universitaires de Strasbourg, France.

出版信息

Ann Thorac Surg. 1995 Jan;59(1):196-200. doi: 10.1016/0003-4975(94)00728-P.

Abstract

From January 1, 1978 to December 31, 1992, 37 patients underwent a completion pneumonectomy after a previous lobectomy (36 men and 1 woman; mean age, 60 years; range, 41 to 77 years). These account for 4.8% of 758 pneumonectomies. The purpose of the present study was to evaluate the operative results of completion pneumonectomy and long-term survival in patients with bronchogenic cancer. The initial lung resection had been performed for primary bronchogenic cancer in 23, metastatic thyroid adenocarcinoma in 1, and benign diseases in 13 (tuberculosis in 11, aspergilloma in 1, and bronchiectasis in 1). Completion pneumonectomy was required for bronchogenic cancer in 32 (15 stage I, 6 stage II, 11 stage III). One patient had relapsing metastatic thyroid carcinoma, 2 had bronchiectasis, and 2 had a venous infarction after lobectomy. Four patients (10.8%) died perioperatively of the following causes: 1 fatal intraoperative bleeding, 1 fatal postoperative bleeding, 1 pneumonia, and 1 malignant hypercalcemia. Median operative blood loss was 1,000 mL, and 19 patients experienced bleeding exceeding 1,000 mL (51%). Six patients had intraoperative vascular injury. Nonfatal surgical complications occurred in 9 patients (24%), including 5 clotted hemothoraces, 3 empyemas, and 1 bronchopleural fistula. Four patients had medical complications (2 pulmonary edemas, 1 sinus tachycardia, and 1 unexplained fever). Twenty-three had an uneventful straightforward recovery (62%).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1978年1月1日至1992年12月31日,37例患者在先前肺叶切除术后接受了全肺切除术(36例男性和1例女性;平均年龄60岁;范围41至77岁)。这些患者占758例全肺切除术的4.8%。本研究的目的是评估支气管源性癌患者行全肺切除术的手术结果和长期生存率。最初的肺切除术是因为原发性支气管源性癌进行的有23例,转移性甲状腺腺癌1例,良性疾病13例(11例肺结核,1例曲霉菌球,1例支气管扩张)。32例因支气管源性癌需要行全肺切除术(15例I期,6例II期,11例III期)。1例患者有复发性转移性甲状腺癌,2例有支气管扩张,2例肺叶切除术后有静脉梗死。4例患者(10.8%)围手术期死亡,原因如下:1例术中致命性出血,1例术后致命性出血,1例肺炎,1例恶性高钙血症。术中失血量中位数为1000 mL,19例患者失血量超过1000 mL(51%)。6例患者术中发生血管损伤。9例患者(24%)发生非致命性手术并发症,包括5例凝固性血胸、3例脓胸和1例支气管胸膜瘘。4例患者有内科并发症(2例肺水肿,1例窦性心动过速,1例不明原因发热)。23例患者顺利康复(62%)。(摘要截断于250字)

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